氯離子通道具有多種重要的生理和細(xì)胞功能，包括調(diào)節(jié)pH值，體內(nèi)穩(wěn)態(tài)，有機(jī)溶質(zhì)轉(zhuǎn)運(yùn)，細(xì)胞遷移，氯離子通道代表了有價(jià)值的藥品靶標(biāo)。許多慢性病癥狀態(tài)，例如囊性纖維化和Bartter綜合征，是由于氯化物通道功能的缺陷所致。Screen Quest 比色氯通道測(cè)定試劑盒為研究氯離子通道提供了靈敏而穩(wěn)定的比色方法。該測(cè)定法基于我們專有的碘化物指示劑（Iodide Blue ），用于測(cè)量碘化物濃度，該測(cè)定法檢測(cè)到的碘化物低至30 nM。 Screen Quest 氯離子通道測(cè)定試劑盒提供了一種用于檢測(cè)氯離子通道的優(yōu)化測(cè)定方法。該測(cè)定可以使用96孔或384孔微孔板進(jìn)行，并易于適應(yīng)自動(dòng)化。百螢生物是AAT Bioquest的中國(guó)代理商，為您提供的Screen Quest 比色法氯離子通道檢測(cè)試劑盒。
參考文獻(xiàn)
A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response
Authors: Pirri JK, McPherson AD, Donnelly JL, Francis MM, Alkema MJ.
Journal: Neuron (2009): 526
ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification
Authors: Stephan AB, Shum EY, Hirsh S, Cygnar KD, Reisert J, Zhao H.
Journal: Proc Natl Acad Sci U S A (2009): 11776
Activation of a chloride channel by a trophic ligand is required for development of the mouse preimplantation embryo in vitro
Authors: Li Y, O'Neill C, Day ML.
Journal: Biol Reprod (2009): 759
An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus
Authors: McCavera S, Rogers AT, Yates DM, Woods DJ, Wolstenholme AJ.
Journal: Mol Pharmacol (2009): 1347
Chloride intracellular channel 1 regulates osteoblast differentiation
Authors: Yang JY, Jung JY, Cho SW, Choi HJ, Kim SW, Kim SY, Kim HJ, Jang CH, Lee MG, Han J, Shin CS.
Journal: Bone (2009): 1175
Chloride intracellular channel protein-4 functions in angiogenesis by supporting acidification of vacuoles along the intracellular tubulogenic pathway
Authors: Ulmasov B, Bruno J, Gordon N, Hartnett ME, Edwards JC.
Journal: Am J Pathol (2009): 1084
Chloride intracellular channel-4 is a determinant of native collateral formation in skeletal muscle and brain
Authors: Chalothorn D, Zhang H, Smith JE, Edwards JC, Faber JE.
Journal: Circ Res (2009): 89